26+ min ago  (144+ words) A genomic language model called res Lens could help researchers spot antibiotic resistance genes that conventional database-matching tools may miss, offering a faster route to tracking emerging resistance while highlighting the need for careful validation. Study: res Lens: genomic language…...

2+ hour, 18+ min ago  (628+ words) A mouse mast-cell study reveals a striking split between two engineered nanoparticles: Si O2 dampened antigen-triggered allergic activation in vitro, while m Ti O2 showed cytotoxic and pro-inflammatory effects. Study: Examining the immunomodulatory role of nanoparticles on mast cell activation. Image Credit:…...

3+ hour, 58+ min ago  (829+ words) A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6 A methylation, in the development and progression of a wide range of diseases, including cancer, metabolic disorders, and cardiovascular conditions. The article highlights…...

2+ day, 3+ hour ago  (584+ words) University of Cincinnati'structural biologists are the first in the world to visualize a key cell protein as part of newly published research from the'College of Medicine. The Seegar Lab'has become the first to visualize the structure of a regulator protein,…...

2+ day, 3+ hour ago  (148+ words) Introduction The author questions whether cancer has been misrepresented by overspecialization. Od H views cancer as an adaptive, self'learning evolutionary process that can be managed by AI'engineered p53 superproteins. Cancer as Biological Fatalism Standard oncology: cancer arises from mutations in cell…...

2+ day, 3+ hour ago  (991+ words) Marine organisms have evolved a remarkable arsenal of host-defense peptides under conditions of extreme variability and constant pathogen exposure. Generally defined as short chains of 2 to 20 amino acid residues, these molecules have become a focal point for biomedicine, food science,…...

2+ day, 3+ hour ago  (525+ words) As neuroscience strives for generalizability and equity, understanding human brain diversity across populations is crucial. Brain functional differences reflect anatomy, lifestyle, and environmental influences As neuroscience strives for generalizability and equity, understanding human brain diversity across populations is crucial. To…...

2+ day, 9+ hour ago  (315+ words) A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T lymphocytes against viruses and tumors. Dendritic cells are immune cells that detect threats and…...

2+ day, 10+ hour ago  (261+ words) A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping. Cells communicate through secreted signaling proteins that regulate metabolism, immunity, development, and tissue repair. But for many of these…...

2+ day, 11+ hour ago  (280+ words) The weight-loss benefits of GLP-1s are well documented and scientists generally know the brain regions associated with these effects. However, several questions remain, such as why responses to medication differ between patients and why the effects for most eventually plateau....