News
Can AI do neuroscience without understanding?
1+ hour, 39+ min ago (224+ words) Prediction without understanding sustained astronomy through a thousand years of epicycles. Artificial intelligence is now offering neuroscience the same deal. Artificial intelligence (AI) is prying them apart. Consider Alpha Fold. Its predictive accuracy is extraordinary. But there is no explanatory…...
Psilocybin rewires specific mouse cortical networks in lasting ways
4+ mon, 3+ week ago (324+ words) Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops. A single dose of psilocybin leads to widespread network-specific changes to cortical circuitry in mice, according to a new study published today…...
What Trump's psychedelics executive order means for basic neuroscience
3+ day, 1+ hour ago (595+ words) The order provides a potential path to remove some psychedelic drugs from the strictest regulatory category, yet it "may not be the breakthrough the basic research community has been looking for," says neuroscientist Shawn Lockery. Last Saturday, President Donald Trump…...
Switching neural code may solve ongoing face-recognition debate
4+ day, 1+ hour ago (727+ words) Face patch cells in macaque monkeys initially respond to images of any object but rapidly transition to attend to faces exclusively, a new study finds. Face-selective neurons in the macaque visual cortex dynamically change their tuning properties, according to a…...
To understand decision-making, we need to truly challenge lab animals
1+ week, 1+ hour ago (218+ words) Complex, multidimensional tasks that unfold over time could reveal how different brain areas work together to support decisions. Second, animals perform simple tasks quickly, generating only a narrow window of neural activity from which to try to make sense of…...
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
1+ week, 4+ day ago (510+ words) Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2 A and DYRK1 A variants specifically, a new open-source platform revealed. Hundreds of compounds counteract specific behavioral effects of autism-linked gene variants in zebrafish, according to a new study that, its authors say,…...
What neuroscientists want from a new NINDS director
1+ week, 4+ day ago (114+ words) The search is underway for the next director of the U. S. National Institute of Neurological Disorders and Stroke, who will face a range of challenges, neuroscientists say, but will also have an "immense opportunity to do good things." Neuroscientists across the…...
Arousal neuron activity explains brain blood flow in mice
1+ week, 4+ day ago (589+ words) The findings could influence how researchers interpret signals from techniques that use blood flow as a surrogate for neuronal activity. That active neurons boost nearby blood flow is well known'and widely exploited by neuroimaging techniques to estimate neuronal activity. But…...
This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli
1+ week, 6+ day ago (252+ words) A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence…...
Error equation predicts brain's ability to generalize
2+ week, 3+ day ago (338+ words) Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests. The brain effortlessly tackles countless variations of the same task. A person walking around…...