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News
Wiley releases database combining two of the world’s most trusted chemical identification resources
59+ min ago (213+ words) Wiley, a global leader in authoritative content and research intelligence, today released the new edition of the Wiley Registry/NIST Mass Spectral Library, a reference database that combines two essential mass spectrometry references in a single, integrated collection, giving scientists…...
New human tissue chips aim to replace animal testing
11+ hour, 28+ min ago (300+ words) Immunotherapies heighten the immune system's ability to detect and kill cancer cells. But they can produce adverse effects such as cytokine release syndrome (CRS)-an inflammatory response that can lead to organ failure-and immune effector cell-associated neurotoxicity syndrome (ICANS), which…...
New machine learning model improves accuracy of prenatal genetic testing
11+ hour, 39+ min ago (232+ words) Dr. Rosanna Weksberg, Clinical Geneticist and Senior Associate Scientist, Genetics & Genome Biology at The Hospital for Sick Children (SickKids) Members of the Weksberg lab are experts in epigenetics, the study of factors that influence how genes are turned on and…...
New computational tool identifies hidden genes driving asthma
13+ hour, 59+ min ago (349+ words) One of the biggest challenges in genetics is determining which genes actually drive disease rather than simply being associated with it. DANDELION was designed to address that challenge by identifying genes that contribute directly to disease but are often missed…...
Scientists identify parasite-specific protein linked to chronic Toxoplasma infections
14+ hour, 7+ min ago (350+ words) Toxoplasma gondii, or Toxoplasma, is a parasite that infects hundreds of millions of people around the world. Although cases are often mild, it can cause severe symptoms in in people with weakened immune systems and developing fetuses. It can also…...
Researchers identify molecular targets to treat painful nerve neuromas
17+ hour, 44+ min ago (314+ words) Human peripheral nerves have a remarkable ability to regenerate after damage. However, when re-growing axons fail to meet their target organ, they can transform into painful neuromas. Researchers identify molecular targets to treat painful nerve neuromas Human peripheral nerves have…...
Researchers introduce framework for understanding how emotional content influences people online
17+ hour, 50+ min ago (318+ words) Every day, billions of people scroll through social media posts, online reviews and news feeds filled with emotional content - from glowing five-star reviews to rage-inducing social media rants. Those emotions can quietly shape what people buy, what they believe and…...
Advancing RNA drug discovery with Cryo-EM
21+ hour, 48+ min ago (506+ words) The perception of RNA as an ‘undruggable’ target is rapidly changing. Advancements in computational instruments, combined with diversification in compound mode of action, have started to produce promising results with the arrival of the first FDA-approved RNA-targeting compound (risdiplam) on…...
Study uses alternative splicing data to predict protein function
1+ day, 11+ hour ago (193+ words) A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome. Yet despite decades of research, scientists still struggle to determine the specific biological functions of individual isoforms, many of which…...
Study reveals how wind helps animals track hidden odors
1+ day, 12+ hour ago (783+ words) Humans trust dogs to help find missing people and bees to pollinate their crops. But scientists still don't fully understand how these animals use their extraordinary sense of smell to locate the source of an odor. New University of Colorado…...