News
Redox-neutral ketone'olefin coupling enabled by mild ketone-to-ketyl-type radical conversion - Nature Chemistry
10+ hour, 49+ min ago (1306+ words) Nature Chemistry (2026) Cite this article Mc Daniel, R. et al. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products. Proc. Natl Acad. Sci. USA 96, 18461851 (1999). Foley, D. J. & Waldmann, H. Ketones as strategic building blocks for the…...
Rapid H2 O2-free, radical-and oxygen-driven proximity labeling in living cells and in vivo - Nature Chemical Biology
10+ hour, 49+ min ago (247+ words) Nature Chemical Biology (2026) Cite this article We developed ROProx, a blue-light-activated, H2 O2-free proximity labeling technology that uses the chemical probe BN2 and leverages the intrinsic tyrosyl radical of the peroxidase APEX2. Taking advantage of a dual-brake mechanism, ROProx enables rapid capture of…...
How common bacteria fasten their armour
10+ hour, 49+ min ago (124+ words) Researchers have identified the molecular machinery used by a common bacterium to fasten its outer membrane to its cell wall1. Receive 52 print issues and online access only $3. 83 per issue Substrate selectivity of the human RNA m5 C methyltransferase NSUN2 Article 27 MAY 26 Move over,…...
Gold keeps glittering courtesy of surface chemistry
10+ hour, 49+ min ago (146+ words) Gold (front) tends not to oxidize, unlike the more reactive silver (back). Credit: David Gray/Bloomberg Creative/Getty Atoms on the surface of solid gold spontaneously arrange themselves in ways that prevent oxygen from tarnishing the metal, researchers have found1. Receive…...
Author Correction: Hidden states and dynamics of fractional fillings in twisted Mo Te2 bilayers
10+ hour, 49+ min ago (0+ words) ...
Immune-competent new approach methodologies for a hybrid future - Nature Immunology
10+ hour, 49+ min ago (347+ words) Nature Immunology (2026) Cite this article In a shifting regulatory landscape that increasingly favors organ-on-chip and human cell-based systems, embedding immune complexity is essential to advance new approach methodologies beyond reductionist models and toward a hybrid ecosystem that integrates animal studies....
Author Correction: US oil and gas system emissions from nearly one million aerial site measurements
10+ hour, 49+ min ago (0+ words) ...
Bridget Ogilvie obituary: parasitologist who championed biomedical labs and scientific evidence
1+ day, 10+ hour ago (480+ words) Anne Cooke is emeritus professor of immunobiology at the University of Cambridge, UK. She knew Bridget throughout her career, as a friend and as a recipient of Wellcome Trust fellowships and grants. Credit: David Porter/Fairfax Media via Getty Bridget…...
Daily briefing: The known protein universe just got a lot bigger
2+ day, 10+ hour ago (70+ words) A new AI tool has generated an atlas of more than one billion predicted protein structures. Plus, a biology lab run by ten robots and whether we can truly trust eyewitness accounts during criminal trials. A new AI tool has…...
Share the highs and lows of your career in science: take Nature's global survey
1+ day, 10+ hour ago (40+ words) Science and society are undergoing rapid change. Nature wants to know how this is affecting careers, workplace culture and salaries. Science and society are undergoing rapid change. Nature wants to know how this is affecting careers, workplace culture and salaries....