4+ mon, 2+ day ago  (281+ words) In a newly published paper in Nature Communications, co-senior and co-corresponding authors Yuval Itan, Ph D, Avner Schlessinger, Ph D, and colleagues reported on the development and evaluation of V2 P. The team showed that V2 P's predictions were able to identify pathogenic…...

4+ mon, 3+ week ago  (432+ words) Missense variants'remain'a challenge in genetic interpretation due to their subtle and context-dependent effects. While current prediction models perform well in known disease genes, generalizability is limited in unknown areas of the proteome.' In a new study published in'Nature Genetics titled,…...

4+ mon, 1+ week ago  (347+ words) Credit: Design Cells / i Stock / Getty Images Plus "The Nobel prize was awarded for identifying regulatory T cells, or Tregs, and their role in immune tolerance, without knowing what triggers them," noted'Edgar Engelman, MD, Ph D, a'pathology professor at'Stanford, a…...

1+ week, 4+ day ago  (479+ words) genengnews. com Microplastics have become a defining environmental signature of modern life, turning up in oceans, soil, food, drinking water, and even the air. But their biological fate inside the human body remains far less understood. A new study suggests…...

1+ mon, 1+ week ago  (520+ words) Islet of langerhans, light micrograph. This structure (centre), found in the pancreas, secretes the hormones insulin and glucagon, which control blood sugar levels. Magnification: x200 when printed at. .. Stable glucagon-like peptide-1 receptor (GLP-1) agonists, like Exendin-4 and Ozempic, have become a…...

1+ day, 3+ hour ago  (886+ words) A new gene'editing strategy programs hematopoietic stem cells to produce therapeutic antibodies and other proteins. The approach generates long'lasting immunity in mice and could point to single'vaccine treatments for diverse diseases in the future. The post Stem Cell Editing Programs…...

1+ day, 10+ hour ago  (488+ words) Proteins. 1 launches to commercialize a technology enabling ultra-sensitive detection of proteins at the single-molecule level, with the aim of transforming early disease diagnostics. The post Proteins. 1 Launches to Develop Single Molecule Protein Amplification Tech for Diagnostics appeared first on GEN…...

4+ hour, 40+ min ago  (274+ words) This e Book brings together a curated collection of resources to help you break through the constraints of throughput, reproducibility, and the significant hands-on time required just to keep experiments moving. The post For What's Next: Preparing Today's Lab or…...

1+ day, 5+ hour ago  (403+ words) Cells and tissues have a multitude of methods for intercellular communication. Nanoscale assemblies that transfer proteins and RNAs between cells are known, but the impacts of external additions or synthetic materials is unclear. Researchers from the University College of Dublin's'Centre…...

1+ day, 10+ hour ago  (375+ words) By pinpointing the neural circuits and peptides behind placebo pain relief, scientists showed effects that span pain types, highlighting possible treatment approaches that could avoid opioids altogether. The post Brain Circuits Underlying Placebo Pain Relief Identified in Mice appeared first…...