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News
Sample collection: the overlooked key to genomic study success
1+ hour, 15+ min ago (687+ words) Sample collection strategy can have a significant impact on the success of genomic studies. As studies become larger, more geographically distributed and technically demanding, stabilised saliva collection offers a practical way to support recruitment and logistics while maintaining sample quality…...
Why more ribosomes can mean less protein in mRNA therapeutics
21+ hour, 16+ min ago (1388+ words) What happens when the cellular machinery making a therapeutic protein slows down? New research published in Nature shows how mRNA chemistry can create ribosome traffic jams, affecting both the amount and accuracy of protein production. The success of a messenger…...
UK’s first AI-robotic organoid lab opens in Liverpool
1+ day, 1+ hour ago (596+ words) The Liverpool Accelerate Laboratory will deploy AI-driven robotics alongside human organoid models to advance infectious disease research at scale. Source: Liverpool School of Tropical Medicine A new £20 million high-security robotic laboratory designed to accelerate research into deadly infections and diseases…...
OutSee secures £50k innovate UK grant for AI target validation
1+ day, 20+ hour ago (429+ words) OutSee has secured £50,000 through Innovate UK’s Investor Partnership Grant to pilot an agentic AI sub-system that will automate early-stage triage of drug targets generated by Nomaly, its core AI genomics platform. Genomics and drug discovery company OutSee has secured £50,000 in…...
Insilico launches specialist AI models for drug discovery chemistry
1+ week, 19+ hour ago (387+ words) The models were developed through Insilico’s MMAI Gym for Science framework, which trains compact language models on groups of related scientific problems rather than relying on general-purpose capabilities. Insilico said the approach is intended to address areas such as ADMET…...
Patient-derived tumour organoid biobank maps cancer gene dependencies
1+ week, 23+ hour ago (464+ words) Researchers have developed a new biobank containing 256 tumour organoids grown directly from patient cancer samples, providing a detailed resource for studying how different cancers depend on particular genes. The study, published in Nature, involved tumour samples from patients with colorectal,…...
From antibody discovery to development: long-read sequencing in practice
1+ week, 2+ day ago (272+ words) What if sequencing could become a unified, in-house capability across the biotherapeutic pipeline? By the end of the session, attendees will gain practical examples of how Pfizer is expanding the role of genomics across its discovery funnel and leveraging Oxford…...
Six assay requirements every researcher using NAMs should know
1+ week, 2+ day ago (515+ words) As new approach methodologies (NAMs) move into mainstream drug discovery, advanced models are demanding more from the assays used to measure them. Discover the six requirements for generating reliable, reproducible and biologically meaningful data. As drug development shifts towards new…...
How rare genetic variants could uncover new drug targets
2+ week, 1+ day ago (1241+ words) Most common traits are influenced by many genetic variants with small effects. A new study suggests that unusually high or low levels of traits such as cholesterol or blood pressure may instead be driven by rare genetic variants with much…...
How AI-driven systems biology will reset the starting line for drug development
2+ week, 3+ day ago (340+ words) AI is accelerating drug discovery, yet attrition rates remain high. Its greatest impact may lie not in finding drugs faster, but in helping researchers understand the complex biology driving disease. If AI is making drug discovery dramatically faster, why isn’t…...