19+ min ago  (1194+ words) In a groundbreaking study recently published in Genes & Diseases, researchers from Jilin University have unveiled a pivotal mechanism controlling the metastatic potential of colorectal cancer (CRC) through the molecular interplay between UBR5, an E3 ubiquitin ligase harboring a HECT domain, and Snail,…...

39+ min ago  (889+ words) In the rapidly evolving landscape of optoelectronic technologies, metal halide perovskite light-emitting diodes (PeLEDs) have emerged as highly promising candidates for next-generation display applications due to their remarkable external quantum efficiency (EQE), facile color tunability, and cost-effective fabrication processes. Despite…...

1+ hour, 9+ min ago  (908+ words) In the relentless pursuit of advancing asymmetric catalysis, one of the most daunting obstacles researchers face is the identification of catalyst classes capable of optimizing enantioselectivity for novel reactions. This challenge escalates dramatically when the reaction involves different combinations of…...

1+ hour, 19+ min ago  (129+ words) Notably, the oncogenic capacities of USP30-AS1 are uncoupled from its neighboring gene USP30, emphasizing the autonomous and independent regulatory role that antisense lncRNAs can possess. This decoupling is vital, as it negates the potential confounding influence of the protein-coding gene on cellular…...

1+ hour, 29+ min ago  (842+ words) In the ongoing battle to safeguard honeybee colonies from one of their most formidable adversaries, varroa mites, groundbreaking research conducted by scientists from the USDA Agricultural Research Service (ARS) and the University of California, Davis (UC Davis) reveals a promising…...

1+ hour, 39+ min ago  (839+ words) In a landmark breakthrough poised to redefine the scope of main-group chemistry, researchers have demonstrated a sophisticated redox catalytic cycle harnessed by aluminium'a metal traditionally sidelined in redox catalysis due to its electronic characteristics. Aluminium, constituting over 8% of Earth's crust,…...

1+ hour, 59+ min ago  (549+ words) In a groundbreaking advancement poised to redefine the landscape of acoustic physics and photonics, researchers have unveiled an ultrabroadband phonon laser frequency comb that surpasses the capabilities of prior acoustic frequency comb technologies. Unlike optical frequency combs, which have long…...

2+ hour, 9+ min ago  (340+ words) Lead researcher Sapir Yiflach elucidated the conceptual breakthrough underpinning Learn-to-Steer, stating, "Rather than imposing our assumptions on how the AI should interpret spatial cues, we let the model's own reasoning guide us. By decoding and gently steering the model's thought…...

2+ hour, 19+ min ago  (905+ words) Glioblastoma stands as one of the most devastating and treatment-resistant forms of brain cancer, characterized by rapid proliferation and aggressive invasion into surrounding brain tissue. Current treatment protocols, which typically combine maximal surgical resection, radiation therapy, and chemotherapy using temozolomide,…...

2+ hour, 39+ min ago  (1324+ words) In a landmark move to accelerate the deployment of advanced nuclear technologies, the U.S. Department of Energy's Oak Ridge National Laboratory (ORNL) has entered into a $27 million strategic partnership with Kairos Power, a pioneering clean energy company. This collaboration aims to…...