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News
Tiny RNA Molecule Pushes Schistosome Parasites Toward Self-Destruction
6+ min ago (73+ words) A single microRNA molecule may help determine whether the parasitic blood fluke Schistosoma japonicum thrives inside its host or succumbs to programmed cell death, according to a new study published in Acta Parasitologica. Researchers led by Yuanzhao Sun and Haoran…...
Proteomic Aging Clocks Enter the Clinic in Landmark Phase 2a Geroprotection
6+ min ago (744+ words) For decades, the central obstacle to testing therapies that slow human aging has been painfully simple: aging takes decades to measure. A drug that genuinely delays the biological processes of aging would need years, often a lifetime, of follow-up before…...
Brain cells that protect nerve fibers can turn harmful with age
4+ hour, 54+ min ago (943+ words) A surplus of insulating brain cells, low on one protective protein, tracked the steepest cognitive decline in adults followed since childhood. After 70, memory and quick thinking slow down for most people, and the usual explanation is that the brain’s wiring…...
Castration Reshapes Meat Quality and Muscle Metabolites in Black Tibetan
16+ min ago (117+ words) High on the Qinghai-Tibet Plateau, where flocks of Black Tibetan sheep graze at altitudes of roughly 3,000 meters in China’s Qinghai Province, a routine husbandry practice is quietly rewriting the biochemical identity of one of the region’s most prized meats. Castration…...
Epigenetic Age Tests Face Expert Backlash Over Reliability, Privacy and
27+ min ago (68+ words) Aging has become a product. Across North America and Europe, companies now sell direct-to-consumer epigenetic tests that estimate a customer’s biological age from DNA methylation patterns, often bundled with supplements and lifestyle programs marketed as capable of slowing or even…...
Epigenetic Enzyme Keeps Spinal Disc Cells Metabolically Balanced, Study
27+ min ago (631+ words) Deep inside the intervertebral disc — the resilient cushion that sits between the vertebrae of the spine — a small population of cells works quietly for decades to keep the tissue functional....
Commentary Challenges Claims of Exceptional Melflufen Responses in Multiple
56+ min ago (746+ words) A new commentary published in the Journal of Cancer Research and Clinical Oncology is challenging how exceptional individual responses to an experimental multiple myeloma drug should be interpreted, warning that remarkable case reports can inadvertently obscure evidence that a treatment…...
Hidden Protein Bosses the Cleanup Crew That Keeps Lupus at Bay
56+ min ago (76+ words) Every second of every day, billions of your cells quietly die. Far from being a catastrophe, this mass dying is part of the body’s routine housekeeping, and a specialized force of immune cells stands ready to devour the wreckage. Macrophages,…...
Gut Bacteria May Reveal Brain Aging Decades Before Symptoms Appear
1+ hour ago (636+ words) The earliest fingerprints of an aging brain may be visible not in memory lapses or mood changes, but in an unexpected place: the gut....
Bispecific Antibody Meets Antibody-Drug Conjugate in Promising Small Cell
1+ hour, 11+ min ago (770+ words) Small cell lung cancer has long been one of the most difficult malignancies to treat, marked by aggressive growth, early dissemination and a stubborn tendency to develop resistance to standard therapies....