News
PI3Kγ: A New Approach to Respiratory Relief
1+ hour, 35+ min ago (517+ words) Modulating PI3K" cell signaling pathways may minimize toxicity and reduce symptoms of cystic fibrosis, IDP, and COPE Kither Biotech hopes to remedy that situation using a new approach to cell signaling modulators to inhibit the gamma isoform of phosphatidylinositol 3-kinase (PI3K). Its…...
Spectroscopic PAT for Real-Time Molecular Fingerprinting
1+ hour, 48+ min ago (353+ words) By Lyufei Chen, PhD To overcome the inner filter effect (IFE) in concentrated samples, A-TEEM uses absorbance data to mathematically correct fluorescence intensities. This linearizes the response from ppb to mg/mL, enabling label-free, specific quantification of key components like…...
Scarab Genomics and Bionova Partner to Boost Plasmid DNA Production
3+ hour, 32+ min ago (260+ words) Scarab's Clean Genome platform comprises engineered E. coli strains designed to eliminate mobile genetic elements, minimize genomic instability, and reduce host functions with the goals of higher plasmid yields. The post Scarab Genomics and Bionova Partner to Boost Plasmid DNA Production…...
Digital Tools Benefits Lauded by U.K. Cell and Gene Therapy Accelerator
19+ hour, 31+ min ago (507+ words) By Vivienne Raper, PhD A team from the U.K.s Cell and Gene Therapy Catapult has been using digital tools to aid the manufacturing of autologous therapies, personalized to individual patients, as well as allogeneic therapies that treat a larger patient…...
Bracco Expands into Cell Therapy Space with Lipid-Based Microbubble Technology
21+ hour, 31+ min ago (470+ words) Bracco will be engaging with technology developers, academic research groups, and process development teams at cell therapy companies to evaluate the performance of its microbubble technology across use cases. The post Bracco Expands into Cell Therapy Space with Lipid-Based Microbubble…...
Biomanufacturing Framework for Scaling and In-Line Monitoring
23+ hour, 31+ min ago (329+ words) The Biomanufacturing Training and Education Center at NC State University. [NC State University] A biomanufacturing framework addresses the challenges of scaleup and scaledown, enabling biomanufacturers to scale more quickly and efficiently, whether they're going from bench- to pilot-scale, or enhancing…...
Knowledge Graphs Tame Glycan Complexity
23+ hour, 31+ min ago (506+ words) Fragmented glycosylation evidence is transformed into a bioprocessing-ready knowledge graph, using text mining to link cell-culture parameters with glycan outcomes. This interactive interface reveals direct and indirect relationships for smarter process development. The post Knowledge Graphs Tame Glycan Complexity appeared…...
Fast Booming AI in Biopharma Needs Essential and Clear Regulations
23+ hour, 31+ min ago (506+ words) By Gareth John Macdonald Artificial intelligence (AI) is now an essential tool in biopharma manufacturing, yet industry still needs guidelines on how LLMs, ML, and other technologies should be used in drug making, say the authors of a new study....
New Antibody Targets Bacterial Sugar to Combat Drug‑Resistant Infections
1+ day, 2+ hour ago (909+ words) By designing antibodies that recognize pseudaminic acid, the scientists were able to clear lethal infections in mice'offering a potential new strategy for tackling multidrug'resistant pathogens. The post New Antibody Targets Bacterial Sugar to Combat Drug'Resistant Infections appeared first on GEN…...
Cellares to Automate Manufacturing and Release Testing for Gene-Edited HSC Therapies for Stanford Medicine
1+ day, 14+ hour ago (331+ words) Researchers are developing gene-edited hematopoietic stem cells as potentially one-time treatments that rebuild the blood and immune system with corrected cells for patients with HIV and rare inherited diseases. The post Cellares to Automate Manufacturing and Release Testing for Gene-Edited…...