2+ day, 12+ min ago   (272+ words) A protein better known for its role in immune checkpoint signaling may help harmful aging cells, or senescent cells, remain hidden from the immune system, allowing them to accumulate in tissues and contribute to age-related dysfunction, according to a new…...

2+ day, 3+ hour ago   (361+ words) A Salk Institute team has now discovered a novel pathway that links chronic interferon II (IFN-II) exposure to mitochondrial dysfunction that ultimately causes immunosuppression. By explaining how interferon II turns from “good” to “bad,” the foundational insights provide a path…...

2+ day, 6+ hour ago   (433+ words) By Mike May, PhD A key to modern media optimization comes from knowing that different cell types need different media. [Westend61 / Getty Images] Cell culture has come a long way since then. That complexity was the focus of a recent discussion…...

2+ day, 7+ hour ago   (441+ words) As wet-lab validation becomes increasingly important to support artificial intelligence-enhanced science, research science points out that human-relevant cell models provide an important foundation for testing and confirming AI-generated insights. The post Revvity Signs Agreement to Acquire Human Cell Design appeared…...

3+ day, 4+ hour ago   (430+ words) Scientists developed monoclonal antibodies targeting matrix metalloproteinase-9, which in a newly reported preclinical study slowed and even reversed diabetic nerve damage in mouse models of type I and type II diabetes. The post Monoclonal Antibodies Targeting MMP-9 Alleviate Peripheral Neuropathy…...

4+ day, 33+ min ago   (485+ words) Genetic Engineering and Biotechnology News For decades, RAS proteins have occupied a frustrating place in cancer biology: central to tumor growth, yet difficult to drug. Members of the RAS family—KRAS, NRAS, and HRAS—act as molecular switches that help…...

4+ day, 3+ hour ago   (372+ words) AI can now generate drug candidates faster than labs can test them, shifting pharma’s challenge from molecular design to experimental validation Sponsored content brought to you by Artificial intelligence is dramatically accelerating early drug discovery. Models can screen chemical space,…...

4+ day, 7+ hour ago   (52+ words) Sponsored content brought to you by 1. Clarke H, et al. Biotechnol Prog. 2024:e3449. doi:10.1002/btpr.3449. 2. Diep J, et al. Biotechnol Prog. 2021;37:e3192. doi:10.1002/btpr.3192. 5. Corrigall H. Bruker Cellular Analysis webinar, 2025. Eric Sackmann, PhD, is a director of product management at Bruker Cellular Analysis....

1+ week, 1+ day ago   (344+ words) Researchers headed by a team at the Centre for Kidney and Bladder Health, Division of Medicine, University College London, have used a novel human 3D micro-bladder model to demonstrate how phage therapy could help to reduce recurrent urinary tract infections (UTIs),…...

1+ week, 1+ day ago   (266+ words) This work was published in Science in the paper, “Early-life colonization with Clostridioides difficile remodels the developing gut.” C. diff causes symptoms ranging from diarrhea to deadly colonic inflammation caused by the production of toxins. It spreads quickly via spores…...