Focused search for science

Curated, credible results

4Sciences helps users find science-focused information, products, and tools. Built by search architects and domain specialists, the platform combines multiple indexes, specialized ranking algorithms, and AI systems to return relevant, credible science content. Use the site to search literature, news, vendors, data, and practical resources. Part of the 4SEARCH network of topic specific search engines.

This 194-Year-Old Tortoise Has the Cells of a 5-Year-Old

Saint Helena, a remote island in the South Atlantic Ocean, is home to Jonathan, an elderly Aldabra giant tortoise who was brought there long ago from the Seychelles. Although Jonathan is 194 years old, his physiology tells a different story. According to his cells, Jonathan has the biological age of a five-year-old tortoise. A new study published in Science Advances found that Jonathan is working with a toolbox of anti-aging cells unlike any seen before. Researchers from the University of Cambridge and the Kaleel Foundation determined this after collecting Jonathan's DNA, sequencing it, and identifying 287 unique gene variants. The gracefully aging tortoise, which was alive during the time of Charles Darwin and Queen Victoria, has cells that "repair damaged DNA, reduce inflammation, regulate insulation," and even keep cancer at bay. Jonathan the giant tortoise is 194 years young, thanks…

1,170 words2 outlets
More in Fields and Topics

Innovent Announces NMPA Acceptance of a New Indication Application of Sintilimab for the Treatment of Advanced Melanoma

SAN FRANCISCO and SUZHOU, China, Oct. 26, 2026 /PRNewswire/ -- Innovent Biologics, Inc. ('Innovent') (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of cancer, metabolic, autoimmune and other major diseases, today announced that a New Indication Application for sintilimab in combination with Nolgileucel injection (GC101) has been accepted for review by the China National Medical Products Administration (NMPA). The application is proposed to be sintilimab in combination with Nolgileucel Injection (GC101) for the treatment of patients with unresectable or metastatic melanoma whose disease has progressed following at least two lines of prior systemic therapy, including PD-1 antibody therapy. This would be the 11th indication for sintilimab, further consolidating its position as a cornerstone…

1,042 words4 outlets
More in Biology, Genetics and Medicine

CityUHK researchers reveal how fructose can suppress liver cancer, opening a new therapeutic avenue

Fructose is an important nutrient, which despite having a chemical structure very similar to that of glucose, is metabolised very differently in the body. Research into fructose metabolism and its regulation of metabolism in the human body has in recent years become a frontier topic in the life sciences and medicine. A new study led by researchers at City University of Hong Kong (CityUHK) has found that in the specific metabolic context of hepatocellular carcinoma (HCC), dietary fructose does no Oops, something went wrong CityUHK researchers reveal how fructose can suppress liver cancer, opening a new therapeutic avenue HONG KONG, Oct. 26, 2026 /PRNewswire/ -- Fructose is an important nutrient, which despite having a chemical structure very similar to that of glucose, is metabolised very differently in the body. Research into fructose metabolism and its regulation of metabolism in the…

853 words2 outlets
More in Research and Discoveries
gcn.com

Intel’s new laptop chips flip their power wiring to the back of the silicon, and the company says an early test version of that design hit 90 percent cell utilization

Flip a laptop over and nothing about the hinge or the keyboard hints at what just changed underneath the lid. Inside the processor, the wiring itself has been turned around. Power no longer travels the same path as the signals telling the chip what to compute. Instead it arrives from the opposite side of the silicon entirely. That rerouting just shipped inside millions of new laptops. So how does flipping the wiring actually make a chip faster? For decades, every wire on a processor, the ones carrying electrical current and the ones carrying data, shared the same side of the silicon. As transistors shrank, those two jobs started fighting for the same real estate, and cramped signal paths began losing ground to the fatter wires that power needs to avoid overheating. The fix is almost mechanically simple once you see it: flip the chip’s power network to the underside of the wafer and…

799 words
More in Technology and Tools