Focused search for science

2+ min ago (275+ words) The Original Plan vs. Reality In my previous post, I planned to step into LLM orchestration by contributing to LangChain or diving into full-stack development with Django. However, digging into the codebase made me realize a distinct difference in engineering styles. Rediscovering the Joy of Data Engineering Naturally, I shifted my focus back to Dagster. Scanning the issue tab, I found myself drawn to problems that dealt with strict data flow and orchestration logic. It wasn't just because Dagster was familiar, it was because the challenges were genuinely more stimulating. For instance, working on a feature that required learning Polars was exciting, even though it was a completely new library for me. This confirmed my preference: "I enjoy the process when working on the concrete logic of data processing rather than the abstraction layers of LLM applications." Choosing Depth Over…...

5+ min ago (74+ words) [Techmeme permalink] Wall Street Journal: Sources: Masayoshi Son plans with the White House to build "Trump Industrial Parks" in the US to produce AI infrastructure parts, funded by Japan's trade deal" " SoftBank billionaire seeks to build "Trump Industrial Parks" on federal land, using hundreds of billions of capital from the Japan trade deal This is a Techmeme archive page. It shows how the site appeared at 11:15 PM ET, December 4, 2025....

5+ min ago (399+ words) The 'unexpected and suspicious' breach introduced hidden background code to the app SmartTube, a widely used YouTube client for Android TV, recently faced a serious compromise after an attacker gained access to the developer's signing keys. This breach allowed a malicious update to reach users without any warning, adding a secret native library known as libalphasdk.so [VirusTotal]. Assessment of version 30.51 shows that the hidden library does not appear in the open-source codebase. This raised a red flag, since the file ran in the background, registered the device with a remote server, and maintained communication without alerting the user. The incident surfaced when Play Protect flagged the app and blocked installations, which triggered immediate concerns across the community. Yuriy Yuliskov, the developer of SmartTube, confirmed that an attacker had taken his keys and had added harmful code to the app....

6+ min ago (353+ words) Scientists in China revived Einstein's 1927 challenge with a single-atom setup, reaffirming Bohr's rule and opening fresh quantum paths. Quantum physics just delivered a full-circle moment a century in the making. A team of researchers at University of Science and Technology of China (USTC)" has reconstructed one of Albert Einstein's most famous attempts to poke holes in quantum theory, and the results land squarely in Niels Bohr's camp. Using an exquisitely sensitive single-atom interferometer, researchers led by Pan Jianwei have brought Einstein's 1927 thought experiment into the real world with unprecedented precision. Their setup shows, once again, that the quantum world refuses to let us see everything at once. Bohr countered that the universe simply doesn't work that way as some of its properties are fundamentally incompatible in a single measurement. Nearly 100 years later, the Chinese team found nature siding with Bohr....

11+ min ago (157+ words) The AI agent ecosystem is growing quickly, and engineers often face confusion when selecting the right tools for experimentation, automation, or production workloads. This post provides a simple decision flow that helps you understand where each tool fits and how to choose the right framework for your current stage of development. Understanding the AI Agent Tooling Landscape The visual above outlines two practical categories of tools: experimental and production ready. Each category supports different goals, and choosing the correct one improves reliability, clarity, and long term maintainability. This flowchart simplifies the decision process: If you want to experiment or explore, start with flexible research tools. If you want to deploy agent workflows in real environments, use production ready orchestrators and data frameworks. If the main requirement is user interaction, choose chatbot focused frameworks. Choosing the right tool at the right…...

12+ min ago (730+ words) Unlike traditional hair supplements that only provide basic vitamins, Nutrafol uses a science-backed, holistic approach to improve hair growth from within. With thousands of success stories and clinical studies supporting its formulation, Nutrafol has changed how women understand hair health. Nutrafol Women is not just another multivitamin. It is a physician-formulated, research-driven supplement that targets the multiple triggers behind hair thinning. In women, hair loss is rarely caused by just one issue. It is often linked to a combination of: " " Hormonal imbalance " " Chronic stress and high cortisol " " Postpartum changes " " Thyroid fluctuations " " Nutritional gaps " " Inflammation in the scalp Nutrafol Women addresses all of these root causes together, making it one of the most effective solutions for long-term hair growth. The formula includes botanical extracts, anti-inflammatory agents, collagen peptides, and clinically proven adaptogens'creating a complete internal support system for the hair. This…...

16+ min ago (592+ words) Most medical office voice agents break when patients reschedule mid-call or ask about insurance. Here's how to build one that handles real appointment logic'not just "press 1 for scheduling." What you'll build: A HIPAA-aware voice agent that connects Twilio's phone infrastructure to VAPI's conversational AI, with function calling to your EHR system for real-time slot availability. Outcome: Patients book, modify, or cancel appointments via natural conversation'no hold music, no "press 9 to repeat." API Access & Authentication: Twilio: Get Twilio Voice API " Get Twilio Most medical office integrations fail because they treat VAPI and Twilio as a single system. They're not. VAPI handles the conversational AI. Twilio routes the phone calls. Your server bridges them. Critical separation of concerns: Create the assistant via VAPI Dashboard or API. Dashboard is faster for initial setup. Use API for production deployments. Assistant config (set in VAPI…...

18+ min ago (861+ words) En este art'culo comparto c'mo interceptar mensajes de ventana en WinUI 3 usando interop con Win32, para bloquear la acci'n de maximizar cuando el usuario hace doble clic en el title bar. Objetivo Evitar que la ventana principal se maximice al hacer doble clic en la barra de t'tulo, manteniendo el resto de comportamientos intactos. [objetivo] C'digo completo using Microsoft.UI.Windowing; using Microsoft.UI.Xaml; using System; using System.Runtime.InteropServices; using Windows.Graphics; using WinRT.Interop; namespace TestApp.WinUI3 { /// /// An empty window that can be used on its own or navigated to within a Frame. /// public sealed partial class MainWindow : Window { private readonly IntPtr _hwnd; private readonly IntPtr _oldWndProc; private delegate IntPtr WndProcDelegate(IntPtr hWnd, uint msg, IntPtr wParam, IntPtr lParam); private readonly WndProcDelegate _newWndProc; private const uint WM_NCLBUTTONDBLCLK = 0x00A3; private const int GWLP_WNDPROC = -4; public MainWindow() { InitializeComponent(); AppWindow.TitleBar.PreferredTheme = TitleBarTheme.UseDefaultAppMode; ExtendsContentIntoTitleBar = true; SetTitleBar(titleBar); OverlappedPresenter?...

19+ min ago (1085+ words) In every production RAG system I've been asked to review from financial knowledge systems to enterprise search to chatbot backends, I've seen one pattern repeat itself: Embedding drift silently breaks retrieval while everyone blames the model. By the time people notice that answers have become inconsistent or incomplete, the drift has already spread across the entire pipeline. And yet embedding drift is rarely discussed. It's not glamorous. It's not "research exciting." It doesn't feel like deep skill work. So it gets overlooked. But if you've ever wondered why your RAG pipeline feels stable one month and unreliable the next embedding drift is almost always the culprit. Let's break this down the way I explain it to AI teams during audits. 1. What Is Embedding Drift? (The Real Definition) Embedding drift occurs when: The same text produces different embeddings over time due…...

19+ min ago (1109+ words) In multiple preclinical models of PARPi-resistant ovarian cancer a treatment strategy combining PARPi with the indirect WNT inhibitor SM08502 significantly reduced disease progression, remodeled the tumor immune microenvironment, and extended survival. The post Combination Therapy for PARPi-Resistant Ovarian Cancer Progresses to Clinical Development appeared first on GEN - Genetic Engineering and Biotechnology News. Researchers at the University of Colorado (UC) Denver, Anschutz Medical Campus, have discovered a novel combination treatment strategy that could offer new hope to ovarian cancer patients who stop responding to existing PARP inhibitor (PARPi) therapies. The strategy combines a PARP inhibitor, a targeted drug used to treat certain types of ovarian cancer, with a novel indirect WNT inhibitor, SM08502 (cirtuvivint), to attack cancer from two directions. SM08502 is a dual CDC-like kinase and dual-specificity tyrosine phosphorylation'regulated kinase inhibitor. In a newly reported study, the researchers report on tests evaluating therapy…...